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Microbiology 3453
Immunology
September, 1998
Practice Quiz

Complete the following.

1. The Turks conferred immunity by injecting ___________________ into the veins of        persons desiring immunity.
2. Edward Jenner immunized James Phipps with pustular material from Sarah Nelms        who had _________ sores. James became immune to ____________.
3.  _________ is a measure of the disease-producing power of an organism.
4.  __________ means lessening of virulence.
5.  Louis Pasteur injected chickens with the cholera organism (now called Pasteurella        multocida) but the chickens did not die. At a later date these same chickens were     injected with a fresh culture of Pasteurella multocida but again the chickens survived        because ______________________________.
6.  Injection of dried rabies material for 14 days in succession induced ___________        before the viable rabis virus had its effects on the dog-bitten Joseph Meister.
7. Match the following:
a. Naturally acquired active immunity     ____ Anti-toxin to human who stepped on a nail.
b. Naturally acquired passive immunity  _____ Virus vaccine to human.
c. Artificially acquired active immunity    _____Antibodies from the milk of a mother.
d. Artificially acquired passive immunity _____ Immunity from having measles.
                                                                     _____Injection of tetanus toxoid to a horse.
                                                                     _____Antibodies that cross the placenta.
8.    The fluid collected from clotted blood is called _________________. The fluid of whole blood is called ___________________.
9.   Attenuation can be accomplished by ___________________, _______________,         or by growing the microbe at a temperature other than its normal temperature for         growth.
10. The first experience of an animal with an antigen results in a response called the          _________________________ in which low levels of antibodies are produced. A          second experience with the same antigen results in an exaggerated response          which goes by the names ________________, ____________________,               ______________________, or ________________________.

Microbiology 4453

Immunology

First One-Hour Exam

Practice Questions

Name: ________________________

Each question may have more than one correct answer. Read each item carefully and record the correct answers on a Scantron answer sheet. Wrong choices are deducted from your overall score.

1. Vaccination using cowpox (vaccinia) was first described by

a. Louis Pasteur               b. Lady Mary Montagu            c. Emil von Behring          d. Edward Jenner                e. Paul Ehrlich

2. The primary immune response

a. can be induced by one dose of antigen.

b. is characterized by a long lag period.

c. results in low levels of antibodies produced.

d. has a rapid decline phase.

e. is characterized by high production of IgG.

3. A secondary immune response

a. occurs after several months following the first encounter with antigen.

b. has a very short lag period.

c. is mediated by cells such as macrophages.

d. only occurs against toxoids.

e. can be easily induced by the first encounter with one high dose of antigen.

4. Passive immunization against tetanus toxin

a. utilizes immune serum obtained from a different animal than the host.

b. induces specific antibodies in the recipient against the toxin.

c. requires injection of tetanus toxoid into the person at risk.

d. was a procedure first introduced by Karl Landstiener.

e. confers long lasting immunity against the toxin.

5. Disulfide bonds can be formed

a. between peptide chains as well as within a single peptide chain.

b. between glycine and serine residues.

c. between two different peptide chains only.

d. between peptides and nucleic acids.

e. within residues on a single peptide chain only.

6. Which of the following is/are not immunogenic?

a. bovine serum albumin         b. bacterial lipopolysaccharide              c. glucose d.      nylon                                       e. coal dust

7. Which of the following properties do not influence the antigenecity of a molecule?

          a. conformation                         b. complexity                                             c. color            d.    stability                                    e. molecular weight