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UTEP to Work on Solutions to Reduce Drug Use-Related HIV in the El Paso-Ciudad Juárez Border Region

Last Updated on December 17, 2021 at 2:00 PM

Originally published December 17, 2021

By Laura L. Acosta

UTEP Marketing and Communications

The University of Texas at El Paso will develop a sustainable public health intervention to suppress human immunodeficiency virus (HIV) in people who use drugs in the El Paso-Ciudad Juárez border region to help slow the spread of HIV. The initiative will be funded by a $3 million grant from the National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA).

UTEP faculty member Julia Lechuga, Ph.D., will collaborate with Programa Compañeros in Juárez, Mexico, on a study to suppress HIV in people who use drugs in the El Paso-Ciudad Juárez border region. Lechuga, center, is pictured with Programa Compañeros staff members, from left, Maria Elena Ramos, Rebeca Ramos, Maria Luisa Gonzalez and Jocelyn Hernadez. Bottom row, from left, are Luisa Ramos, Alejandro Ortiz and David Montelongo. Photo: Courtesy of Julia Lechuga
UTEP faculty member Julia Lechuga, Ph.D., will collaborate with Programa Compañeros in Juárez, Mexico, on a study to suppress HIV in people who use drugs in the El Paso-Ciudad Juárez border region. Lechuga, center, is pictured with Programa Compañeros staff members, from left, Maria Elena Ramos, Rebeca Ramos, Maria Luisa Gonzalez and Jocelyn Hernadez. Bottom row, from left, are Luisa Ramos, Alejandro Ortiz and David Montelongo. Photo: Courtesy of Julia Lechuga

Julia Lechuga, Ph.D., UTEP associate professor of public health sciences, received funding to implement a biobehavioral intervention aimed at suppressing the viral load of HIV in people who inject drugs so that the probability of HIV forward transmission is reduced. The recently funded study is the next phase of Project Encuentro, a community-based HIV risk-reduction program in El Paso and Juárez, Mexico, that Lechuga established with support from another NIH grant she received in 2016. Project Encuentro is a collaboration between UTEP and Programa Compañeros, a Juárez-based social service organization.

“Despite advances in HIV treatment, people are still at risk for getting and transmitting the virus, particularly people who inject drugs,” said Lechuga, who joined the UTEP College of Health Sciences in 2019. “Our aim is to reduce the spread of HIV in our binational community by providing people who use drugs access to much-needed resources to help them improve their health and their quality of life.”

According to the Centers for Disease Control and Prevention, adults and adolescents who inject drugs accounted for 10% of the 37,968 new HIV diagnoses in the United States, U.S. territories and the Republic of Palau in 2018. Substance use can lead to risky behaviors such as sharing needles or having unprotected sex, thereby increasing the chances of getting HIV and transmitting the virus. 

Researchers, which include faculty from the University of California, San Francisco, will use a new multiphase optimization strategy to develop an intervention to improve adherence to antiretroviral therapy among 384 HIV-positive people who use drugs in Juárez.

If taken exactly as prescribed, antiretroviral therapy can lower the amount of virus, or viral load, in the blood to undetectable levels.

Over the next five years, Lechuga will test four interventions to determine which combinations are most effective at helping people who inject drugs and who are HIV-positive to suppress their viral load. Strategies include using patient navigators to help participants obtain HIV treatment services, providing psychological therapy to treat depression, improving access to methadone treatment, and offering educational sessions and skills for medication adherence.

Maria Elena Ramos, executive director of Programa Compañeros, said this new project will allow the organization to implement new interventions to assist individuals who inject drugs and who are living with HIV adhere to medication by providing new public health strategies such as psychological therapies.

“This new study will allow us to adapt evidence-based practices and incorporate them into other effective treatment models,” Ramos said. “We will also learn about other tools to detect and treat the most prevalent mental health conditions such as depression in the population that we serve.”

Lechuga participated in a similar intervention to Project Encuentro in San Salvador, the capital of El Salvador, between 2010 and 2015. The success of the program prompted Lechuga, an El Paso native, to adapt the intervention to target people who use drugs in El Paso and Juárez. She received a five-year NIH grant to fund the program through 2021.

Over the past five years, Project Encuentro has directly impacted 3,500 people on both sides of the U.S.-Mexico border. The program provided HIV testing to people who inject heroin or crack, and offered peer network interventions and educational sessions to reduce HIV risk among people who use drugs.

Funding from the first NIH grant ended earlier this year. Lechuga said another aim of the new NIH NIDA grant would be to help Programa Compañeros build its capacity to sustain the program even after the grant funding has expired.

This would allow Programa Compañeros to continue providing much needed services to reduce HIV in the community, particularly among people who use drugs who are least likely to access HIV prevention and treatment because of the stigma surrounding substance use.

William H. Robertson, Ph.D., interim dean of the College of Health Sciences said Lechuga’s research provides pathways to understanding the factors needed in treating the whole individual as a member of our community, especially in terms of addressing public health conditions, such as HIV or Hepatitis C.

“A fundamental mission of the College of Health Sciences is to serve our local community and to become embedded within the community with our teaching, research and service,” Robertson said. “Dr. Lechuga’s work exemplifies this importance of an integrative approach to addressing public health as community-based issues first and foremost.”