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Selected Publications

• Baily, P.T.; Del Castillo, H.P.; Vinales, I.; Urbay, J.E.M.; Paez, A.; Weaver, M.R.; Iturralde, Estevao, I.L.; R.; Jankuru, S.R.; Almeida, I.C.; Li, C.; Dirk, C.W.; Michael, K., Synthesis and Photoreactivity of 7-Nitroindoline-S-thiocarbamates, ACS Omega 2023, DOI: https://pubs.acs.org/doi/10.1021/acsomega.2c08184

 

• Montoya, A.L.; Carvajal, E.G.; Ortega-Rodriguez, U., Estevao, I.L.; Ashmus, R.A.; Jankuru, S.R.; Portillo, S.; Ellis, C.C., Knight, C.D.; Alonso-Padilla, J.; Izquierdo, L.; Pinazo, M.-J.; Gascon, J.; Suarez, V.; Watts, D.M.; Malo, I.R.; Ramsey, J.M.; Alarcón De Noya, B.; Noya, O.; Almeida, I.C.; Michael, K., A branched, double alpha-Gal-bearing synthetic neoglycoprotein as a biomarker for Chagas disease, Molecules, 2022, 27, 5414, DOI: https://doi.org/10.3390/molecules27175714

 

• Montoya, A.L.; Gil, E.R.; Heydemann, E.L.; Estevao, I.L.; Luna, B.E.; Ellis, C.C.; Jankuru, S.R.; Alarcón de Noya, B.; Noya, O.; Zago, M.P.; Almeida, I.C; Michael, K., Specific Recognition of β-Galactofuranose-Containing Glycans of Synthetic Neoglycoproteins by Sera of Chronic Chagas Disease Patients, Molecules 2022, 27, 411, DOI: https://doi.org/10.3390/molecules27020411

 

• Montoya, A.L; Austin, V.M.; Portillo, S.; Vinales, I.; Ashmus, R.A.; Estevao, I.; Jankuru, S.R; Alraey, Y.; Al-Salem, W.S.; Acosta-Serrano, A.; Almeida, I.C.; Michael, K., "Reversed Immunoglycomics Identifies α-Galactosyl-Bearing Glycotopes Specific for Leishmania major Infection", JACS Au, 2021, 1 (8) , 1275-1287, DOI: 10.1021/jacsau.1c00201.

 

• Portillo, S.; Zepeda, B.G.; Iniguez, E.; Olivas, J.J.; Hosseini, N.K.; Moreira, O.C.; Marques, A.F.; Michael, K.; Maldonado, R.A.; Almeida, I.C. “α-Gal-based prophylactic glycovaccine effectively protects against experimental Chagas disease”, npj Vaccines 2019, 4:13, DOI: 10.1038/s41541-019-0107-7 .

 

• Ortega-Rodriguez, U.; Portillo, S.; Ashmus, R.A.; Duran, J.A.; Schocker, N.S.; Iniguez, E.; Montoya, A.L.; Zepeda, B.G.; Olivas, J.J.; Karimi, N.H.; Alonso-Padilla, J.; Izquierdo, L.; Pinazo, M.-J.; Alarcón de Noya, B.; Noya, O.; Maldonado, R.A.; Torrico, F.; Gascón, J.; Michael, K.; Almeida, I.C. “Purification of glycosylphosphatidylinositol-anchored mucins from Trypanosoma cruzi trypomastigotes and synthesis of a-Gal-containing neoglycoproteins: application as biomarkers for reliable diagnosis and early assessment of chemotherapeutic outcomes of Chagas disease”, Methods Mol. Biol. 2019; 1955:287-308, DOI: 10.1007/978-1-4939-9148-8_22 .

 

• Subramaniam, K.; Austin, V.; Schocker, N.S.; Montoya, A.L.; Mesri, M.; Al-Salem, W.; Almeida, I.C.; Michael, K. Acosta-Serrano, A. “Anti-alpha-Gal antibodies detected by novel neoglycoproteins as diagnostic tool for Old World cutaneous leishmaniasis caused by Leishmania major”, Parasitology 2018, 145 (13), 1758-1764, DOI: 10.1017/S0031182018000860 .


• Ornelas, A.; Williams, K.N.; Hatch, K.A.; Paez, A.; Aguilar, A.C.; Ellis. C.C.; Tasnim, N.; Ray, S.; Dirk, C.W.; Boland, T.; Joddar, B.; Li, C.; Michael, K. “Synthesis and characterization of a photocleavable collagen-like peptide”, Org. Biomol. Chem. 2018, 16, 1000 – 1013, DOI: 10.1039/C7OB02198D .

 

• Iniguez, E.; Schocker N.S.; , Subramaniam, K.; Portillo, S.; Montoya, A.L.; Al-Salem, W.S.; Torres, C.L.; Rodriguez, F.; Moreira, O.C.; Acosta-Serrano, A.; Michael, K.; Almeida, I.C.; Maldonado, R.A. “An a-Gal-containing neoglycoprotein-based vaccine partially protects against murine cutaneous leishmaniasis caused by Leishmania major” PLoS Negl. Trop. Dis. 2017, 11(10):e0006039, DOI: 10.1371/journal.pntd.0006039 .

 

• Hatch, K.A.; Ornelas, A., Williams, K.N., Boland, T.; Michael, K.; Li, C.-Q. “Photolysis of a peptide with N-peptidyl-7-nitroindoline units using two-photon absorption” Biomed. Optics Express 2016, 7, 4654-4659,  DOI:  10.1364/BOE.7.004654.


• Schocker, N.S.; Portillo, S.; Brito, C.R.N.; Marques, A.F.; Almeida, I.C., Michael, K. "Synthesis of Galα(1,3)Galβ(1,4)GlcNAcα-, Galβ(1,4)GlcNAcα-, and GlcNAcα-containing neoglycoproteins and their immunological evaluation in the context of Chagas disease” Glycobiology 2016, 26, 39-50, DOI: 10.1093/glycob/cwv081 .

 

• Pardo, A; Hogenauer, T.J.; Cai, Z.; Vellucci, J.A.; Castillo, E.M.; Dirk, C.W.; Franz, A.H.; Michael, K. “Efficient photochemical synthesis of peptide-a-phenylthioesters” ChemBioChem 2015, 16, 1884-1889, DOI: 10.1002/cbic.201500266 .

 

• Ashmus, R.A.; Schocker, N.S.; Cordero-Mendoza, Y.; Marques, A.F.; Monroy, E.Y.; Pardo, A.; Izquierdo, L.; Gállego, M.;Gascon, J.; Almeida, I.C.; Michael, K. “Potential use of synthetic α-galactosyl-containing glycotopes of the parasite Trypanosoma cruzi as diagnostic antigens for Chagas disease” Org. Biomol. Chem. 2013, 11, 5579-5583, DOI: 10.1039/c3ob40887f .

 

• Khamsi,J.; Ashmus, R.A.; Schocker, N.S.; Michael, K. "A high-yielding synthesis of allyl glycosides from peracetylated glycosyl donors" Carbohydr. Res. 2012, 357, 147–150, DOI: 10.1016/j.carres.2012.05.008 .

 

• Mendez, J.E.; Westfall, N.J.; Michael, K.; Dirk, C.W. “Photoreactivity of an N-acetyl-7-nitroindoline - unraveling the mechanism by computation”, Trends in Photochemistry and Photobiology, 2012, 14, 75-91.

 

• Hogenauer, T.J.; Wang, Q.; Sanki, A.K.; Gammon, A.J.; Chu, C.H.L.; Kaneshiro, C.M.; Kajihara, Y.; Michael, K. “Virtually epimerization-free synthesis of peptide-a-thioesters” Org. Biomol. Chem. 2007, 5, 759-762, DOI: 10.1039/B618442A .

 

• Kaneshiro, C.M.; Michael, K. “A convergent synthesis of N-linked glycopeptides” Angew. Chem. Int. Ed. 2006, 45, 1077-1081, DOI: 10.1021/acs.orglett.6b02288.