Research

ONGOING (SELECTED PROJECTS)

Our lab is actively engaged in several groundbreaking projects:

• Customized orthotic systems development for addressing peripheral neuropathy condition: Proposing a new workflow with computational models and materials evaluation for the development of orthotic boots to reduce the risk of amputation in diabetic patients with foot ulcers.
• Electrochemical cardiac biosensor with wireless capabilities as point-of-care system: Exploring materials and micromachining processes to improve packaging and develop a hermetic sensor to monitor cardiac activity through impedance shift responses.
• Wearable system for sweat biomarkers monitoring: Processing flexible substrates and optimizing metallization process for in-line detection of biomarkers in sweat through microfluidic systems and functionalized microelectrodes.
• Microfabrication of a wearable sleeve to record biosignals from muscles: Designing an EMG sensor array system to regain motor functions in patients with lost limbs under a closed-loop architecture providing real-time feedback.
• In-vitro device to study the following-frequency response and its role in auditive behavior: Proposing additive manufacturing and non-conventional metallization strategies to create a prototype for collection of neural responses under a multi-modal excitation for signal processing and evaluation of cognitive process

FINALIZED (SELECTED PROJECTS)

We take pride in our successfully completed projects that have made significant contributions to the field:

• Mitochondria biosensor development for early disease diagnosis: Developing a 3D MEA architecture to capture impedance and electrophysiology emanating from inner and outer mitochondria membrane to elucidate early indicators of health conditions.
• Phase Change Microsystem for Diagnostics: Developed a microsystem for collecting breath condensate to extract biomarkers for point-of-care diagnostics.
• Biosensor with Electrochemical Impedance Spectroscopy for Actin Protein: Fabricated an impedimetric sensor capable of quantifying Actin protein in bundle form using IDE+Microfluidic systems.
• Microfluidics-Based Virus Detection Device: Created microfluidic chips for virus detection using metal evaporation, soft-lithography, and laser micromilling techniques.
• Multilevel microfabrication of 3D printed microfluidics and liquid metal-based MEAs: Designed multi-level structures implementing additive manufacturing, and multi-phase metallization to create microreactors for controlled assays based on MEA
• Microfabrication of Cardiac Organoids Bioplates: Produced biomedical devices for studying electrophysiological responses from cardiac organoids.
• High-Throughput 3D Microelectrode Arrays: Enhanced the throughput of in-vitro analysis in biomedical applications through optimized 3D printing techniques.